April in Amarillo averages a daily high of 22.2°C with nights around 5.5°C. Expect roughly 5.3 wet days totalling 37mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Amarillo is March–May.
Based on AMARILLO AIRPORT, TX US (11.2km), 1995–2024. 30 years of April data.