May in Cape Coral averages a daily high of 32.1°C with nights around 20.9°C. Expect roughly 8.1 wet days totalling 94.1mm. Generally workable, with some weather to plan around.
Across the year, the best time to visit Cape Coral is November–March.
Based on FORT MYERS PAGE FIELD AIRPORT, FL US (9.1km), 1995–2024. 30 years of May data.