October in Des Moines averages a daily high of 17.8°C with nights around 6.5°C. Expect roughly 8.6 wet days totalling 73.4mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Des Moines is September.
Based on DES MOINES INTERNATIONAL AIRPORT, IA US (8.3km), 1995–2024. 30 years of October data.