April in Gainesville averages a daily high of 27.7°C with nights around 13.2°C. Expect roughly 6.1 wet days totalling 70.8mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Gainesville is October–April.
Based on GAINESVILLE REGIONAL AIRPORT, FL US (6.5km), 1995–2024. 30 years of April data.