April in Irvine averages a daily high of 21.2°C with nights around 12.7°C. Expect roughly 3.3 wet days totalling 12.8mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Irvine is April–November.
Based on SANTA ANA JOHN WAYNE AIRPORT, CA US (4.3km), 1995–2024. 25 years of April data.