May in Irvine averages a daily high of 22°C with nights around 14.9°C. Rain is rare — about 2 wet days and 4.9mm across the month. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Irvine is April–November.
Based on SANTA ANA JOHN WAYNE AIRPORT, CA US (4.3km), 1995–2024. 25 years of May data.