April in Knoxville averages a daily high of 21.4°C with nights around 7.1°C. Expect roughly 10.3 wet days totalling 128.3mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Knoxville is April–May.
Based on KNOXVILLE EXPERIMENTAL STATION, TN US (7.7km), 1995–2024. 28 years of April data.