May in Knoxville averages a daily high of 25.9°C with nights around 12.8°C. Expect roughly 11.1 wet days totalling 115.4mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Knoxville is April–May.
Based on KNOXVILLE EXPERIMENTAL STATION, TN US (7.7km), 1995–2024. 29 years of May data.