October in Knoxville averages a daily high of 22.3°C with nights around 8.3°C. Expect roughly 7.6 wet days totalling 76.1mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Knoxville is April–May.
Based on KNOXVILLE EXPERIMENTAL STATION, TN US (7.7km), 1995–2024. 29 years of October data.