April in La Mesa averages a daily high of 23.9°C with nights around 10.5°C. Expect roughly 3.6 wet days totalling 18.4mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit La Mesa is March–June.
Based on EL CAJON, CA US (9.6km), 1995–2024. 28 years of April data.