November in Winston-Salem averages a daily high of 16.3°C with nights around 4.3°C. Expect roughly 8 wet days totalling 74.6mm. Generally workable, with some weather to plan around.
Across the year, the best time to visit Winston-Salem is April–May.
Based on WINSTON SALEM REYNOLDS AIRPORT, NC US (4.1km), 1995–2024. 25 years of November data.