September in Winston-Salem averages a daily high of 26.8°C with nights around 16.5°C. Expect roughly 9.6 wet days totalling 104.7mm. Comfortable conditions for being outdoors all day.
Across the year, the best time to visit Winston-Salem is April–May.
Based on WINSTON SALEM REYNOLDS AIRPORT, NC US (4.1km), 1995–2024. 24 years of September data.